Janssen. R.G.J.H.

study patient diuretic antihypertensive antihypertensive drugs reason buccal control index sample a-adducin purity index date polymorphism population pharmacy collection signi ficantly thiazide netherland dna purity thiazide diuretics signi response synergy hypertension number pharmo table interaction women fluence non-response participant reference difference buccal cell samples 2009 john wiley result factor variant health determinant –control pharmacogenetic university utrecht synergy index epidemiol buccal swabs blood effect ficantly ischemic heart disease a-adducin variant pharmacy records van wieren-de wijer analysis non-responder record questionnaire a-adducin gene response rate risk factors pharmacogenetic study copyright allele heart alpha-adducin disease maastricht 460trp history genotype subject thiazide diuretic buccal cells diuretic use wieren-de laboratory