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scopus: 24460298800

Luis, T.C.

(Tiago Luis)


catenin wnt 3a development pathway hematopoietic β‑ catenin protein blood expression factor study thymocyte progenitors canonical self-renewal canonical wnt differentiation wnt 3a embryos  cell wnt proteins number ‑cell embryo immunol hematopoiesi function t ‑cell development activation system signal myeloid niche mouse nature ficiency progenitor proliferation result t  cells thymic receptor level capacity stage notch thymu staal multilineage wnt 5a transplantation repopulation liver figure wnt 3a cells t cell development transcription marrow repopulation capacity β- catenin target adult assay lineage difference review canonical wnt pathway wnt 3a fls deletion haematopoietic b-catenin percentage kinase fl ow cytometry defect speci phenotype ␤- catenin binding volume wnt pathway




6 Most Recent Publications

Signal transduction pathways regulating hematopoietic stem cell biology: Introduction to a series of Spotlight Reviews (Article)
Luis, T.C. Killmann, N.M.B. Staal, F.J.T.
2012-01-01
Wnt3a nonredundantly controls hematopoietic stem cell function and its deficiency results in complete absence of canonical Wnt signaling (Article)
Luis, T.C. Naber, B.A.E. Fibbe, W.E. Dongen, J.J.M. van Staal, F.J.T.
2010-07-01
Wnt signaling in hematopoiesis: Crucial factors for self-renewal, proliferation, and cell fate decisions (Article)
Staal, F.J.T. Luis, T.C.
2010-04-01
WNT proteins: Environmental factors regulating HSC fate in the niche (Article)
Luis, T.C. Staal, F.J.T.
2009-10-15
Wnt3a deficiency irreversibly impairs hematopoietic stem cell self-renewal and leads to defects in progenitor cell differentiation (Article)
Luis, T.C. Weerkamp, F. Naber, B.A. Baert, M.R. Haas, E.F. de Nikolic, T. Heuvelmans, S. Krijger, R.R. de Dongen, J.J.M. van Staal, F.J.T.
2009-01-15
WNT signalling in the immune system: WNT is spreading its wings (Article)
Staal, F.J.T. Luis, T.C. Tiemessen, M.M.
2008-08-01
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