Reth, M.

pre-b -65 slp -65 expression tumor pre-b cells b cell development btk /slp chain btkact il -7 b cells level development surface pre-b cell tumors culture lymphoma protein btk-deficient pre-bcr e 41k suppressor tumor suppressor slp -65 / tyrosine kinase differentiation tyrosine cycling presence cytoplasmic absence stage tumor formation igg 3 levels kinase immunol result btk-deficient mice slp -65/btk fraction marker activation cd 43 analysis flow cytometric analysis protein tyrosine phosphorylation mouse spleen pre-b cell lymphomas pre-b cell stage pre-b cell lymphoma splenic b cells receptor cell surface markers slp -65 expression bruton pre-b cell receptor pre-b cell compartment light light chain dot plots www.jem.org bm cells 2000. bm cultures lymphoid cells november formation downloaded journal medicine flow cytometry rearrangement 16 wk tumor suppressors surface expression immunity serum function