Bottino, R.

islet transplantation monkey blood xenotransplantation group islet transplantation porcine c-peptide pig islets insulin level alemtuzumab complement glucose diabetes transplant figure antibody study porcine islets ibmir expression response pittsburgh primates factor therapy graft number effect result pancreatic organ activation tissue cynomolgu survival primate donor cynomolgus monkeys depletion islet tx non-human primates animal journal liver signi function american cooper plasma rejection non-human anti-cd coagulation flammatory reaction university t-cell blood glucose windt porcine c-peptide levels blood glucose levels exogenou table nonhuman xenograft patient administration immunosuppression fl ow cytometry starzl transplantation institute heart blood cells nonhuman primates portal vein hcd 46 difference pancreatic islets