Smetanka, C.

islet monkey transplantation alemtuzumab group porcine blood figure insulin level c-peptide islet transplantation glucose antibody number depletion porcine islets cynomolgus monkeys ibmir cynomolgu diabetes study therapy effect anti-cd islet tx animal complement pig islets transplant fl ow cytometry graft xenotransplantation american porcine c-peptide levels journal lymphocyte depletion primate pittsburgh gt-ko primates administration anti-cd 154 mab repopulation normoglycemia memory lymph nodes table signi lymphocyte heparin immunosuppression dextran sulfate cobra venom factor result ef ficacy treatment infusion value t-cell expression t cells response mycophenolate mofetil cd 4+ induction af finity cd 52 expression function survival tissue dextrose anticoagulation signi ficantly breeder hcd 46 recipient complement activity lymphocytes factor