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chimeric gata 6 endoderm morphogenesi 6-/- epithelial cell differentiation development gata 6 mrna transcription factor chimeric lungs epithelial expression differentiation wild-type embryo lung buds specification protein chimeric embryos morrisey lung development experiment hybridization marker mouse oligonucleotide endoderm specification e 15.5 15.5 result tissue antisense oligonucleotides e 18.5 antisense defect explant stage ttf 1 wild-type lungs blastocyst section probe culture function hogan cc 10 epithelial cells thyroid translation initiation site 18.5 koutsouraki cc 10 expression gata 6-/- chimeric study lung endoderm specification e 12.5 lungs whitsett gata 6. distribution foregut non-chimeric lungs es cells galactosidase activity pattern epithelium arrow genes dev surfactant endodermal mesenchyme non-chimeric formation genet orkin keijzer 12.5 rosa 26 blastocysts room temperature order
9 Most Recent Publications
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The pulmonary mesenchymal tissue layer is defective in an in vitro recombinant model of nitrofen-induced lung hypoplasia
(Article)
Loenhout, R.B. van Tseu, I. Huang, Z. Fox, E.K. Tibboel, D. Post, M.R. Keijzer, R. |
2012-01-01
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Prolonged mechanical ventilation induces cell cycle arrest in newborn rat lung
(Article)
Kroon, A.A. Wang, J. Kavanagh, B. Huang, Z. Kuliszewski, M. Goudoever, J.B. van Post, M.R. |
2011-02-28
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Inflammatory response to oxygen and endotoxin in newborn rat lung ventilated with low tidal volume
(Article)
Kroon, A.A. Wang, J. Huang, Z. Cao, L. Kuliszewski, M. Post, M.R. |
2010-07-01
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Congenital diaphragmatic hernia: Comparison of animal models and relevance to the human situation
(Article)
Loenhout, R.B. van Tibboel, D. Post, M.R. Keijzer, R. |
2009-09-01
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Effect of chemical stabilizers of hypoxia-inducible factors on early lung development
(Article)
Groenman, F. Rutter, M. Wang, J. Caniggia, I. Tibboel, D. Post, M.R. |
2007-09-01
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Hypoxia-inducible factors in the first trimester human lung
(Article)
Groenman, F. Rutter, M. Caniggia, I. Tibboel, D. Post, M.R. |
2007-04-01
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Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs
(Article)
Tuyl, M. van Groenman, F. Wang, J. Kuliszewski, M. Liu, J. Tibboel, D. Post, M.R. |
2007-03-15
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Branching and differentiation defects in pulmonary epithelium with elevated GATA6 expression.
(Article)
Koutsourakis, M. Keijzer, R. Visser, P. Post, M.R. Tibboel, D. Grosveld, F.G. |
2001-07-09
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The transcription factor GATA6 is essential for branching morphogenesis and epithelial cell differentiation during fetal pulmonary development
(Article)
Keijzer, R. Tuyl, M. van Meijers, C. Post, M.R. Tibboel, D. Koutsourakis, M. Grosveld, F.G. |
2001-01-01
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