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patient transplant study abcb 1 transplantation kidney recipient polymorphism nephrotoxicity genotype cyp 3a transplant recipients rejection cyp 3a genotype expression association abcb 1 genotype effect concentration pharmacokinetic allele variability function tac clearance abcc 2 snps transporter result graft abcc 2 tacrolimu functionality pharmacogenetic system drug safety signi test items intrapatient variability cni-induced nephrotoxicity signi ficantly sensitivity abcb 1 expression variant liver hospital fluence protein abcb 1 snps clearance clin pharmacol incidence safety allograft check pharmacol haplotype p-glycoprotein donor cyclosporine speci ficity factor speci treatment order ficity resistance table number f m e t i c abc transporters hospital pharmacists inhibitor intrapatient heart multidrug sirolimu test item blood avascular necrosis level
5 Most Recent Publications
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ATP-binding cassette transporters as pharmacogenetic biomarkers for kidney transplantation
(Article)
Shuker, N. Bouamar, R. Weimar, W. Schaik, R.H.N. van Gelder, T. van Hesselink, D.A. |
2011-10-27
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CYP3A5 genotype is not related to the intrapatient variability of tacrolimus clearance
(Article)
Pashaee, N. Bouamar, R. Hesselink, D.A. Roodnat, J.I. Schaik, R.H.N. van Weimar, W. Gelder, T. van |
2011-06-01
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The pharmacogenetics of calcineurin inhibitor-related nephrotoxicity
(Article)
Hesselink, D.A. Bouamar, R. Gelder, T. van |
2010-08-01
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Functionality test for drug safety alerting in computerized physician order entry systems
(Article)
Sijs, I.H. van der Bouamar, R. Gelder, T. van Aarts, J.E.C.M. Berg, M. Vulto, A.G. |
2010-04-01
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Polymorphisms of the glucocorticoid receptor and avascular necrosis of the femoral heads after treatment with corticosteroids
(Article)
Bouamar, R. Koper, J.W. Rossum, E.F.C. van Weimar, W. Gelder, T. van |
2009-10-01
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