Melis, M.L.

kidney uptake peptide analogue radiolabelled j nucl med somatostatin receptor study imaging radioactivity radiolabelled somatostatin analogues therapy tumour patient retention ep krenning radionuclide radiation animal gelofusine megalin effect 111 in-dtpa-octreotide chapter krenning radiolabelled peptides figure in-dtpa-octreotide lu-dota tumours cancer reduction group result tubules damage r valkema spect injection bf bernard function activity m melis wa breeman octreotide reabsorption protein pp kooij lysine treatment wh bakker control tumor bernard radiopeptide mtc-dmsa protection 99 mtc-mag 3 mechanism 99 mtc-dmsa vivo autoradiography administration amifostine 24 h p.i somatostatin analogues valkema visser toxicity biodistribution section neuroendocrine kidney protection 177 lu breeman netherland radiation dose rolleman cortex tissue