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health productivity productivity costs effect state income respondent study valuation patient income effects evaluation health states value compensation mechanisms health state valuations compensation result treatment absenteeism inclusion cost-effectiveness estimate health state perspective mechanism level instruction model difference productivity cost estimates question version leisure questionnaire table method multiplier effects leisure time multiplier research analysis outcome approach brouwer chapter change impact cancer group exercise sample quality colorectal cancer colorectal eq -5d month friction cost approach problem characteristic decision friction productivity cost inclusion guideline metastatic colorectal cancer health care perspective pharmacoeconomic exclusion depression period intervention cost-effectiveness outcomes 5- fu /lv income loss cost-effectiveness ratio labor ratio review presenteeism health care budget