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Smits, R.

(Ron Smits)


expression tumor mutation cancer protein b-catenin control mouse analysis level tumours colorectal patient liver wnt 5a intestine colon development granule tissue staining model study signi signi ficantly math 1-cre mice figure vector neuron tumour sample pathway epithelial colorectal cancer epithelial cells wnt 5a expression biomarker result 1-cre number ctnnb table msi-h 20 a.a precursor downloaded adult allele prr 15 prr 15 expression manuscript adenomas embryo author b-catenine proliferation l-msc granule neuron precursors desmoid disease hcv replication activity phosphorylation desmoid tumours cerebellar math 1-cre cerebella differentiation apc mutations shrna hnpcc b-catenine 654 ␤- catenin ficantly candidate activation fluid animal ctnnb 1 mutations socs 3 expression biopsy specimens




10 Most Recent Publications

Induced Wnt5a expression perturbs embryonic outgrowth and intestinal elongation, but is well-tolerated in adult mice (Article)
Bakker, E.R.M. Raghoebir, L.J Smits, R. Franken, P.F. Helvensteijn, W. Gurp, L. van Meijlink, F. Valk, M. van der Rottier, R. Kuipers, E.J. Veelen, W. van
2012-09-01
Identification of Familial Adenomatous Polyposis carriers among children with desmoid tumours (Article)
Kattentidt-Mouravieva, A.A. Geurts-Giele, I.R.R. Wagner, A. Krijger, R.R. de Noesel, M.M. van Ven, C.P. van de Ouweland, A.M.W. van den Kromosoeto, J.N.R. Dinjens, W.N.M. Dubbink, H.J. Smits, R.
2012-08-01
Proximal fluid proteome profiling of mouse colon tumors reveals biomarkers for early diagnosis of human colorectal cancer (Article)
Fijneman, R.J.A. De Wit, M. Van Turenhout, S.T. Terhaar Sive Droste, J.S. Mulder, C.J.J. Blankenstein, M.A. Robanus-Maandag, E.C. Smits, R. Fodde, R. Hinsbergh, V.W.M. van Meijer, G.A. Jimenez, C.R. Pourghiasian, M. Piersma, S.R. Pham, T.V. Warmoes, M.O. Lavaei, M. Piso, C. Smit, F. Delis-van Diemen, P.M.
2012-05-01
Severe alterations of cerebellar cortical development after constitutive activation of Wnt signaling in granule neuron precursors (Article)
Lorenz, A. Deutschmann, M. Ahlfeld, J. Prix, C. Koch, A. Smits, R. Fodde, R. Kretzschmar, H.A. Schüller, U.
2011-08-01
Mobilization of hepatic mesenchymal stem cells from human liver grafts (Article)
Pan, Q. Fouraschen, S.M.G. Metselaar, H.J. Kazemier, G. Jonge, J. de Tilanus, H.W. Wagemaker, G. Janssen, H.L.A. Laan, L.J.W. van der Kaya, F.S.F.A. Verstegen, M.M.A. Pescatori, M. Stubbs, A. IJcken, W.F.J. van Van Der Sloot, A. Smits, R. Kwekkeboom, J.
2011-05-01
Disturbance of the microRNA pathway by commonly used lentiviral shRNA libraries limits the application for screening host factors involved in hepatitis C virus infection (Article)
Pan, Q. Ruiter, P.E. de Von Eije, K.J. Smits, R. Kwekkeboom, J. Tilanus, H.W. Berkhout, B. Janssen, H.L.A. Laan, L.J.W. van der
2011-04-06
β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis (Article)
Veelen, W. van Le, N.H. Kuipers, E.J. Fodde, R. Smits, R. Helvensteijn, W. Blonden, L. Theeuwes, J.J.M. Bakker, E. Franken, P.F. Gurp, L. van Meijlink, F. Valk, M.A. van der
2011-02-09
Expression analysis of proline rich 15 (Prr15) in mouse and human gastrointestinal tumors (Article)
Meunier, D. Patra, K. Fundele, R.H. Smits, R. Hägebarth, A. Lüttges, A. Jaussi, R. Wieduwilt, M.J. Quintanilla-Fend, L. Himmelbauer, H. Fodde, R.
2011-01-01
Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability (Article)
Albuquerque, C. Baltazar, C. Rodrigues, P. Veiga, I. Ramos, J.S. Fonseca, I. Leitão, C.N. Fodde, R. Filipe, B. Penha, F. Pereira, T. Smits, R. Cravo, M. Lage, P. Fidalgo, P. Claro, I.
2010-08-01
A new conditional Apc-mutant mouse model for colorectal cancer (Article)
Robanus-Maandag, E.C. Koelink, P.J. Breukel, C. Salvatori, D.C.F. Jagmohan-Changur, S.C. Bosch, C.A.J. Verspaget, H.W. Devilee, P. Fodde, R. Smits, R.
2010-02-22