Lewis, V.

survival disease patient creutzfeldt –jakob disease onset codon prion study mutation protein creutzfeldt signi table –jakob codon 129 gender month surveillance prpsc effect signi ficantly signi ficance locus prpsc type brain analysis fluence number department fication health prnp gene duration prion protein gene codon 129 polymorphism codon 129 genotype polymorphism 14-3-3 university model neurol variable crude reference iatrogenic v 210i patients country wilcoxon test multivariate 10 years ficantly analyses ficant neurology group creutzfeldt-jakob disease fi ndings e 200k 14-3-3 test spongiform multivariate analysis prion diseases prnp locus cjd patients predictor multiplication germany variant collin erasmus mc university subtype ficance therapy nding pocchiari univariate prion protein feature illness prion disease