Smit, L.S.

plasma mutation sample patient concentration study solution townes-brocks syndrome syndrome nerve anomaly netherland method −80 ◦ c qc samples protein erasmu myelin stability 2–8 ◦ c 50 ␮ l hypomyelinating neuropathy levetiracetam neuropathy pharmacokinetic volume water townes-brock neonate matrix phase methanol family p.arg 276x mutation matrix effects ucb 17025 seizure precipitation analysis precision effect department phenotype chromatogr column assay rotterdam 1000 ␮ l sall 1 gene sall 1 fi nal protein precipitation inaccuracy calibration 1.50 hospital level condition report father plasma samples ion suppression deviation 7 days 0.5 result pharmacokinetic study infusion fication table phase solution erasmus university chromatography children p.arg response nerve conduction studies suppression composition 2–8