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expression barrier ve-cadherin brain shp 2 spry 1 function protein control catenin β- catenin level tyrosine phosphorylation receptor thrombin nod 2 tyrosine phosphorylation barrier function tumor analysis junction thrombin stimulation stimulation figure study shrna medline development endothelin crossref monocyte monolayer increase result recovery treatment cancer cell –cell junctions tlr 2 experiment epithelial activity disease spry 1 expression epithelial cells hcmec phosphatase activation effect rar  expression kinase pathway rar  cmt 93/69 cells hcmec /d cells mutation resistance blot analysis oncogenic ras antibody rh 30 cells spry 1 levels inhibitor brain ecs inhibition oncogenic 93/69 netherland flammatory journal etb receptor ligand knockdown –cell blood-brain barrier monocyte diapedesis domain blood erms cells
5 Most Recent Publications
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Retinoic acid induces blood-brain barrier development
(Article)
Mizee, M.R. Wooldrik, D. Vries, H.E. de Reijerkerk, A. Lakeman, K.A.M. Hof, B. van het Drexhage, H.A. Geerts, D. Bugiani, M. Aronica, E. Mebius, R.E. Prat, A. |
2013-01-23
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The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation
(Article)
Timmerman, I.S.K. Hoogenboezem, M. Bennett, A.M. Geerts, D. Hordijk, P.L. Buul, J.D. van |
2012-11-01
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Nod2 improves barrier function of intestinal epithelial cells via enhancement of TLR responses
(Article)
Hiemstra, I.H. Bouma, G. Geerts, D. Kraal, G. Haan, J.M.M.D. |
2012-06-29
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Brain endothelial barrier passage by monocytes is controlled by the endothelin system
(Article)
Vries, H.E. de Hof, B. van het Kooij, Gijs Reijerkerk, A. Lakeman, K.A.M. Wijck, Y. van Geerts, D. Drexhage, J.A.R. |
2011-07-01
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Silencing of SPRY1 triggers complete regression of rhabdomyosarcoma tumors carrying a mutated RAS gene
(Article)
Schaaf, G. Hamdi, M. Zwijnenburg, D. Lakeman, A. Geerts, D. Versteeg, R. Kool, M. |
2010-01-15
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