Peters, B.J.M.

statin study index date polymorphism allele control patient abcb 1 slco 1b interaction effect index association response haplotype genotype carrier pharmacogenetic exposure variant participant pharmacy records gnb 3 gene record ischemic heart disease pharmacy protein disease population abcb 1 gene t allele carriers research subunit group article infarction risk reduction table slco 1b gene transporter status hypertension pharmacogenomic statin therapy variability cholesterol therapy calcium channel blockers pharmo statin treatment region pharmacokinetic 0.39 result statin use –control synergy index science 0.72 cohort future simvastatin case –control status gnb 3t allele method subject c 825t polymorphism treatment atorvastatin 0.37 sample factor antihypertensive lipid response figure 0.38 0.41 0.45 effectiveness atherosclerosi