Soler, E.

binding region ldb 1 expression protein interaction transcription binding sites factor analysis control locus figure promoter number igk locus sequence pre-b differentiation transcript lymphoma pre-b cells hrs cells experiment csf 1r 1-cre complex hrs cell lines element development hodgkin chip-seq recombination enhancer identi target erythroid sequencing segment method level fication cbfa 2t expression cbfa 2t cell lines vk gene segments genomic chromatin binding site genome vh 81x pro-b ficient activation target genes b cells immunity nature soler hematopoietic usage position 220+cd speci germline eto 2 ctcf-de b-globin rearrangement absence grosveld fragment non-hodgkin b cell development result activity zebra fish embryos hl -60 cells igk enhancer interactions motif