Desai, R.K.

protein transcription effect ros 17/2.8 cells level expression vitamin library erasmus mc receptor osteocalcin binding promoter stein activity interaction vdr protein levels growth factor complex element van wijnen aj treatment stein jl osteoblast basal op gene expression osteopontin assay response 17/2.8 lian jb enhancement oc transcription mechanism vdr /rxr heterodimers control stein gs presence vdr protein op vdres modulation differentiation transfection result erasmu oc gene expression op transcription december transcriptional downloaded library analysis blot analysis bortell r vdr levels reporter cat activity ligand wijnen growth factor beta op gene transcription up-regulation function basal cat activity regulation transfected experiment increase p value calculation 2.5 protein kinase c sequence f 12 medium inhibition hormone heterodimer deluca dihydroxyvitamin vdr mrna levels phenotype