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binding osteocalcin protein osteopontin receptor vitamin transcription ros 17/2.8 cells expression effect 17/2.8 level element activity assay library erasmus mc response nucleotide complex promoter rat osteocalcin vdre vdr /rxr heterodimers stein osteoblast-like rxr ␣ interaction vdr /rxr binding vdr protein levels kh 1060 growth sequence factor vdr /rxr half-site control erasmu extract treatment van wijnen aj stein jl osteoblast study downloaded library ligand basal reporter op gene expression mouse osteopontin vdre experiment hormone heterodimer erasmus mc oc transcription enhancement lian jb table i mechanism mouse transfected deluca 1. data stein gs oligonucleotide vdr protein op vdres presence modulation value differentiation oc gene expression oc /op vdre transfection result dna binding absorbance value op transcription analog experiments ϯ s.e rat osteocalcin
2 Most Recent Publications
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A central dinucleotide within vitamin D response elements modulates DNA binding and transactivation by the vitamin D receptor in cellular response to natural and synthetic ligands.
(Article)
Bemd, G.J.C.M. van den Jhamai, M. Staal, A. Wijnen, A.J. van Lian, J.B. Stein, G.S. Pols, H.A.P. Leeuwen, J.P.T.M. van |
2002-04-26
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Antagonistic effects of transforming growth factor-beta on vitamin D3 enhancement of osteocalcin and osteopontin transcription: reduced interactions of vitamin D receptor/retinoid X receptor complexes with vitamin E response elements
(Article)
Staal, A. Lian, J.B. Leeuwen, J.P.T.M. van Wijnen, A.J. van Desai, R.K. Pols, H.A.P. Birkenhäger, J.C. Deluca, H.F. Denhardt, D.T. Stein, J.L. Stein, G.S. |
1996-01-01
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