Wessels, J.

toxicity telatinib patient polymorphism study association cancer condition treatment pharmacokinetic number contraction grade function pharmacogenetic lippman factor side effects phase p-value parameter genotype receptor transporter target cycle sample inhibitor tumor research space interpatient variability reward respect growth kinase vegfr grade 1–4 toxicity markov decision processes analysis gelderblom h effect supremum process blood samples supremum norm abcg 2 decision table treatment cycles haplotype 1–4 tyrosine netherland gelderblom analyses leiden university genes encoding ugt 1a hypertension tumor types kruskal –wallis test function v blood drug transporters chi-square test telatinib pharmacokinetic data flt 4 genotype leiden stage pharmacogenetic research growth factor supremum norms operator target receptor polymorphisms encoding 150 mg tablets abcb 1 phase i variability