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neuron motor motor neurons protein dynein g 1del mice expression disease bicd 2 section antibody aggregate level control degeneration figure mouse ercc 1d mice ranbp sod 1 neurosci hela cells motor neuron degeneration staining study centrosome sirna motoneuron brain amyotrophic golgi nucleus sclerosis t 3t mice receptor aldolase dorsal mutation analysis dorsal horn transfected number interneuron cerebellar wild-type structure effect immunoreactivity vapb-p dynactin model ret-ir kinesin purkinje bn 1 mice function transport abnormality dendrite ranbp 2 change glyt 2 injury death aldolase c ventral horn t 3hsod mice repair fi bers lamina ubiquitinated onset /dynactin factor vapb-p 56s aggregates cause material motor neuron disease purkinje cells vapb-p 56s
9 Most Recent Publications
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Spinal inhibitory interneuron pathology follows motor neuron degeneration independent of glial mutant superoxide dismutase 1 expression in SOD1-ALS mice
(Article)
Hossaini, S.M. Cano, S.C. Dis, V. van Haasdijk, E.D. Hoogenraad, C.C. Holstege, J.C. Jaarsma, D. |
2011-08-01
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Age-related motor neuron degeneration in DNA repair-deficient Ercc1 mice
(Article)
Waard, M.C. de Pluijm, I. van der Gillingwater, T.H. Jaarsma, D. Zuiderveen Borgesius, N. Comley, L.H. Haasdijk, E.D. Rijksen, Y.M. Ridwan, Y. Zondag, G. Hoeijmakers, J.H.J. Elgersma, Y. |
2010-10-01
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Bicaudal D2, dynein, and kinesin-1 associate with nuclear pore complexes and regulate centrosome and nuclear positioning during mitotic entry
(Article)
Splinter, D. Tanenbaum, M.E. Demmers, J.A. Fornerod, M.W.J. Melchior, F. Hoogenraad, C.C. Medema, R.H. Akhmanova, A. Lindqvist, A. Jaarsma, D. Flotho, A. Yu, K.L. Grigoriev, I. Engelsma, D. Haasdijk, E.D. Keijzer, N. |
2010-04-01
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A novel mouse model with impaired dynein/dynactin function develops amyotrophic lateral sclerosis (ALS)-like features in motor neurons and improves lifespan in SOD1-ALS mice
(Article)
Teuling, E. Dis, V. van Wulf, P. Haasdijk, E.D. Akhmanova, A. Hoogenraad, C.C. Jaarsma, D. |
2008-09-08
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Neuron-specific expression of mutant superoxide dismutase is sufficient to induce amyotrophic lateral sclerosis in transgenic mice
(Article)
Jaarsma, D. Teuling, E. Haasdijk, E.D. Zeeuw, C.I. de Hoogenraad, C.C. |
2008-02-27
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Estradiol improves cerebellar memory formation by activating estrogen receptor β
(Article)
Andreescu, C.E. Milojkovic, B.A. Haasdijk, E.D. Kramer, P. Jong, F.A. de Krust, A. Zeeuw, C.I. de Jeu, M.T.G. de |
2007-10-03
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Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates
(Article)
Teuling, E. Ahmed, S. Haasdijk, E.D. Demmers, J.A. Steinmetz, M.O. Akhmanova, A. Jaarsma, D. Hoogenraad, C.C. |
2007-09-05
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Aldolase C-positive cerebellar Purkinje cells are resistant to delayed death after cerebral trauma and AMPA-mediated excitotoxicity
(Article)
Slemmer, J.E. Haasdijk, E.D. Engel, D.C. Plesnila, N. Weber, J.T. |
2007-08-01
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Distribution of RET immunoreactivity in the rodent spinal cord and changes after nerve injury
(Article)
Jongen, J.L.M. Jaarsma, D. Hossaini, S.M. Natarajan, D. Haasdijk, E.D. Holstege, J.C. |
2007-02-20
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