Siebenga, J.J.

noroviru outbreak variant strain patient sequence capsid virus gastroenteriti study infection number epidemic genotype population surveillance mutation netherland model analysis protein norovirus outbreaks figure noroviruse death polymerase sample virol illness disease region vennema h nucleotide dataset domain health evolution p 2 domain hospital substitution selection capsid protein period analyses table koopman detection cause vennema epidemiology 2006 b variant winter norovirus infections diversity capsid sequences season pathogen trend emergence institute pattern group transmission structure siebenga result recombination norovirus infection 2002 variant koopmans m dynamic 2006 b japan children norovirus gii method immunity prevalence nursing homes hospitalization