pond, S.L.K.

variant sequence capsid epidemic strain dataset model polymerase population selection analysis substitution dynamic virus figure noroviru analyses bayesian number codon outbreak protein evolution polymerase dataset surveillance study nov gii infection structure nucleotide recombination genotype branch vennema h polymerase sequences 2006 b variant region sampling substitution rates capsid dataset diversity pathogen capsid protein mutation detection gastroenteriti 1996 variant value bayesian skyline plot length pressure phylodynamic 2002 variant pattern history distribution volume neutrality issue increase emergence capsid sequences effect 2006 b surveillance data 59 end institute antigenic likelihood estimate approach virol noroviruse influenza simulation method coalescent position class detail