Rodijk, M.

vector expression lentiviral therapy level figure b cells ad 5-gfa number transplantation promoter 5-gfa ficiency gene therapy blood tumor spleen sffv.corag b-cell animal serum btk à/à mice lentiviral vectors leukemia patient rag 1 expression protein 1-/- t cells ficient analysis ficiency yy ng reconstitution transfer adenoviru development sequence wtad 5 btk expression oncolytic transduced infection result spleen cells replication treatment immunode fl ow cytometry sffv.corag 1-treated mice t-cell 19.cobtk lentiviral gene therapy signi efs.cobtk correction control lentiviral gene transfer netherland integration glioma rag 1à/à mice oncolytic ef ficacy transgene cd 19.cobtk gfap-positive transduction codon-optimized b-cell development btk à/à cancer rag 1 immunode ficiency ucoe.corag codon kinase virus tyrosine 1-treated insertional mutagenesis ficacy