Kal, J.A.

variability within-patient variability patient within-patient graft clearance end point study failure graft failure tac clearance concentration transplantation transplant rejection point erasmus universiteit rotterdam graft loss pharmacokinetic allograft nephropathy month outcome tacrolimu kidney factor exposure control number result risk factor creatinine mpa clearance analysis recipient difference table period 12 months allograft nephropathy group post-tx biopsy-proven 1 january 2000 van gelder t rotterdam 12 months post-tx window influence covariate value tacrolimus clearance erasmu graft survival 297 patients kidney transplantation transplant recipients universiteit episode function downloaded intraindividual organ death september correlation tac within-patient variability mycophenolate mofetil year post-tx kidney transplant patients follow-up 31 december 2004 figure 12 months post-transplantation mycophenolic acid tac concentrations population 12 months posttransplantation mpa exposure intraindividual variability