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globin locus mouse expression region chromosome probe transcription analysis deletion fragment sequence globin genes transposition embryo cosmid erythroid - globin gene protein number result erythroid cells promoter gata 6 transposon signal figure grosveld chromatin cyln 2 gene control development level position β- globin gene liver neuron antibody genomic effect tissue globin gene genome globin loci - globin locus wild-type -115 element murine histone transgene - globin promoter adult structure pufferfish domain interaction globin locus transposase factor heterochromatin brain hypersensitive methylated blood staining liver cells blastocyst heart β- globin locus hemoglobin stage hybridization dnasei γ- globin genes d.p.c nucleolu insertion endoderm chromatin structure
10 Most Recent Publications
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Tagged mutagenesis by efficient minos-based germ line transposition
(Article)
Wit, T.P.M. de Dekker, S. Drabek, D.D. Maas, A. Breedveld, G.J. Knoch, T.A. Langeveld, A. Szumska, D. Craig, R. Bhattacharya, S. Grosveld, F.G. |
2010-01-01
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Multiple interactions between regulatory regions are required to stabilize an active chromatin hub.
(Article)
Patrinos, G.P. Krom, M. de Boer, E. de Langeveld, A. Imam, A.M.A. Strouboulis, J. Laat, W.L. de Grosveld, F.G. |
2004-06-15
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Transposition of the Drosophila hydei Minos transposon in the mouse germ line.
(Article)
Drabek, D.D. Zagoraiou, L. Langeveld, A. Roumpaki, C. Mamalaki, C. Savakis, C. Grosveld, F.G. Wit, T.P.M. de |
2003-02-01
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Functional and comparative analysis of globin loci in pufferfish and humans
(Article)
Gillemans, N. Tan-Un, K. Langeveld, A. Higgs, D. Philipsen, J.N.J. Grosveld, F.G. McMorrow, T. Tewari, R. Wai, A.W. Burgtorf, C. Drabek, D.D. Ventress, N. |
2003-01-01
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An intrinsic but cell-nonautonomous defect in GATA-1 overexpressing mouse erythroid cells.
(Letter To Editor)
Whyatt, D. Lindeboom, F.A. Karis, A. Milot, E. Bruijn, M.F.T.R. de Langeveld, A. Hendriks, R.W. Gribnau, J.H. Grosveld, F.G. Philipsen, J.N.J. |
2000-08-03
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Characterisation of transcriptionally active and inactive chromatin domains in neurons
(Article)
Akhmanova, A. Verkerk, T. Langeveld, A. Galjart, N.J. Grosveld, F.G. |
2000-01-01
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Deletion of a region that is a candidate for the difference between the deletion forms of hereditary persistence of fetal hemoglobin and deltabeta-thalassemia affects beta- but not gamma-globin gene expression.
(Article)
Calzolari, R. McMorrow, T. Yannoutsos, N. Langeveld, A. Grosveld, F.G. |
1999-02-15
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The transcription factor GATA6 is essential for early extraembryonic development
(Article)
Koutsourakis, M. Langeveld, A. Patient, R. Beddington, R. Grosveld, F.G. |
1999-01-01
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The Murine CYLN2 Gene: genomic organization, chromosome localization and comparison to the human gene that is located within the 7q11.23 Williams Syndrome Critical Region.
(Article)
Eussen, B.H.J. Langeveld, A. Haperen, R. van Winterberg, S. Wouters, C.H. Grosveld, F.G. Galjart, N.J. Zeeuw, C.I. de Hoogenraad, C.C. |
1998-11-01
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The dynamics of gene expression: frequency and duration of transcription.
(Article)
Milot, E. Strouboulis, J. Fraser, P. Trimborn, T. Wijgerde, M.G.J.M. Boer, E. de Langeveld, A. Tan-Un, K. Vergeer, W. Yannoutsos, N. Grosveld, F.G. |
1996-10-01
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