Flier, W.M. van der

disease alzheimer study testing research dementia / translational genomics genomic diagnosis sample patient alzheimer disease control cerebrospinal fl uid health treatment application factor laboratory biomarker translation research p-tau translational association assay centre genotype elisa allele department variation cerebrospinal level phase variability discovery university group apoe genotype mutation practice translation genet measurement individual center intercv value innotestw prediction difference netherland guideline intercentre effect variant neurol mihaescu population table family carrier trial psychiatry identi result neurology marker review susceptibility non-mendelian apoe ε4 allele min – max risk factors non-mendelian ad 10−6 13.32 quality amyloid response