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cartilage il -6 tissue chondrocyte synovial synovial fluid culture fluid synovial tissue matrix differentiation endochondral effect production endochondral ossi fication arthritis study explant cytokine osteoarthritis fication factor donor endplate defect gag release content mesenchymal collagen regeneration release hypertrophic expression il -6 production model cartilage defects chondrogenic gag content formation growth medium patient level oxygen interleukin degeneration marrow endochondral bone formation grade concentration figure sample engineering subchondral osteoarthritic il -6 levels netherland chondrogenesi research stage change addition inhibition arthritis research hypertrophy result interleukin -6 oa chondrocytes analysis coculture il -6 receptor dna content triamcinolone condition cartilage explants tension receptor 21 days implantation utrecht
5 Most Recent Publications
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Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model
(Article)
Tsuchida, A.I. Beekhuizen, M. Rutgers, M. Osch, G.J.V.M. van Bekkers, J.E.J. Bot, A.G.J. Geurts, T.B.P. Dhert, W.J.A. Saris, D.B.F. Creemers, L.B. |
2012-12-03
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Osteoarthritic synovial tissue inhibits proteoglycan production in human osteoarthritic cartilage
(Article)
Beekhuizen, M. Bastiaansen-Jenniskens, Y.M. Koevoet, W. Saris, D.B.F. Dhert, W.J.A. Creemers, L.B. Osch, G.J.V.M. van |
2011-07-01
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Modulating endochondral ossification of multipotent stromal cells for bone regeneration
(Article)
Gawlitta, D. Farrell, E. Malda, J. Creemers, L.B. Alblas, J. Dhert, W.J.A. |
2010-08-01
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Modulating endochondral ossification of multipotent stromal cells for bone regeneration
(Article)
Gawlitta, D. Farrell, E. Malda, J. Creemers, L.B. Alblas, J. Dhert, W.J.A. |
2010-08-01
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Micro-CT quantification of subchondral endplate changes in intervertebral disc degeneration
(Article)
Rutges, J.P.H.J. Jagt, O.P. van der Oner, F.C. Verbout, A.J. Castelein, R.J.M. Kummer, J.A. Weinans, H.H. Creemers, L.B. Dhert, W.J.A. |
2010-01-01
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