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Brugts, J.J.

(Jasper Brugts)


patient study treatment effect disease perindopril trial heart inhibitor event blood ace-inhibitor artery disease pressure ace inhibitors treatment effect therapy polymorphism europa heart failure level analysis statin benefit hypertension artery reduction infarction result blood pressure mortality pharmacogenetic receptor enzyme treatment benefit failure association function group prevention outcome stroke population response table diabetes progress angiotensin brugt ace inhibition inhibition chapter simoons ml system europa trial placebo 1.00 factor ace-inhibitor therapy research cardiology allele pergene randomized bradykinin investigator baseline figure follow-up treatment bene fit signi boersma e peace surgery microcirculation simoon diabetes mellitus difference genotype ferrari r




10 Most Recent Publications

A pharmacogenetic analysis of determinants of hypertension and blood pressure response to angiotensin-converting enzyme inhibitor therapy in patients with vascular disease and healthy individuals (Article)
Brugts, J.J. Isaacs, A. Remme, W.J. Bertrand, M.E. Ninomiya, T. Harrap, S. Chalmers, J. MacMahon, S. Fox, K. Ferrari, R. Simoons, M.L. Danser, A.H.J. Maat, M.P.M. de Boersma, E.R. Duijn, C.M. van Akkerhuis, K.M. Uitterlinden, A.G. Witteman, J.C.M. Cambien, F. Ceconi, C.
2011-03-01
Statins and all-cause mortality in high-risk primary prevention of patients with cardiovascular risk factors (Article)
Brugts, J.J. Deckers, J.W.
2010-12-13
Statin prescription in men and women at cardiovascular risk: To whom and when? (Article)
Brugts, J.J. Deckers, J.W.
2010-09-01
Tailored therapy of ACE inhibitors in stable coronary artery disease: Pharmacogenetic profiling of treatment benefit (Article)
Brugts, J.J. Boersma, E.R. Simoons, M.L.
2010-08-01
Genetic determinants of treatment benefit of the angiotensin-converting enzyme-inhibitor perindopril in patients with stable coronary artery disease (Article)
Brugts, J.J. Isaacs, A.J. MacMahon, S. Fox, K.M. Ferrari, R. Witteman, J.C.M. Danser, A.H.J. Simoons, M.L. Maat, M.P.M. de Boersma, E.R. Duijn, C.M. van Uitterlinden, A.G. Remme, W.J. Bertrand, M.E. Ninomiya, T. Ceconi, C. Chalmers, J.
2010-08-01
Tailored-therapy of ACE-inhibitors in Coronary Artery Disease: Pharmacogenetic Profiling of Treatment Benefit (Doctoral Thesis)
Brugts, J.J.
2010-02-17
The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials. (Article)
Brugts, J.J. Yetgin, T. Domburg, R.T. van Deckers, J.W. Hoeks, S.E. Gotto, A.M. Shepherd, J. Westendorp, R.G.J. Craen, A.J. de Knopp, R.H. Nakamura, H. Ridker, P.
2009-07-20
The effects of intra-aortic balloon pump support on macrocirculation and tissue microcirculation in patients with cardiogenic shock (Article)
Uil, C.A. den Lagrand, W.K. Ent, M. van der Jewbali, L.S.D. Brugts, J.J. Spronk, P.E. Simoons, M.L.
2009-07-01
The consistency of the treatment effect of an ACE-inhibitor based treatment regimen in patients with vascular disease or high risk of vascular disease: A combined analysis of individual data of ADVANCE, EUROPA, and PROGRESS trials (Article)
Brugts, J.J. Ninomiya, T. Boersma, H. Remme, W.J. Bertrand, M.E. Ferrari, R. Fox, K.M. MacMahon, S. Chalmers, J. Simoons, M.L.
2009-06-01
The rationale and design of the perindopril genetic association study (PERGENE): A pharmacogenetic analysis of angiotensin-converting enzyme inhibitor therapy in patients with stable coronary artery disease (Article)
Brugts, J.J. Maat, M.P.M. de Danser, A.H.J. Simoons, M.L. Boersma, H. Witteman, J.C.M. Duijn, C.M. van Uitterlinden, A.G. Bertrand, M.E. Remme, W.J. Fox, K.M. Ferrari, R.
2009-04-01