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scopus: 6603209399

Krimpen, B.A. van

(Brigitte van Krimpen)


blood clone t cells number sample level patient cancer phoenix blood samples lymphocytes phoenix clone 58 flow cytometry marker assay therapy huvec transduction expression transduced cytometry receptor rtvsup detection method fraction t lymphocytes donor result transduced t cells cd 146 mrna t cells transduced production lamer variation figure immunogene therapy transfer transgene rna levels control range percentage 146-enriched cytometric gene transduction study rcc patients value addition tumor 146+ cd 146+ immunogene phoenix clone 58- culture 1.2 transduction efficiencies rosenberg staining gene-modified t cells nuh 821 cells retrovirus t-cell mrna levels rt-pcr metastatic efficiency sensitivity 0.1 fg cytokine dudley cytolysis bioscience gene-modified strijbo cell transfer therapy pg 13 rtvsup flow cytometric method treatment




4 Most Recent Publications

Long-term stability of T-cell activation and transduction components critical to the processing of clinical batches of gene-engineered T cells (Article)
Lamers, C.H.J. Elzakker, P.M.M.L. van Steenbergen, S.L.C. van Luider, B.A. Groot, C. Krimpen, B.A. van Vulto, A.G. Sleijfer, S. Debets, J.E.M.A. Gratama, J-W.
2013-05-01
mRNA levels of CD31, CD144, CD146 and von Willebrand factor do not serve as surrogate markers for circulating endothelial cells (Article)
Strijbos, M.H. Krimpen, B.A. van Debets, J.E.M.A. Kraan, J. Sleijfer, S. Gratama, J-W. Lamers, C.H.J.
2010-08-01
Parallel detection of transduced T lymphocytes after immunogene therapy of renal cell cancer by flow cytometry and real-time polymerase chain reaction: implications for loss of transgene expression (Article)
Lamers, C.H.J. Gratama, J-W. Pouw, N.M.C. Langeveld, S.C.L. Krimpen, B.A. van Kraan, J. Stoter, G. Debets, J.E.M.A.
2005-12-01
Phoenix-ampho outperforms PG13 as retroviral packaging cells to transduce human T cells with tumor-specific receptors: implications for clinical immunogene therapy of cancer (Article)
Lamers, C.H.J. Willemsen, R.A. Elzakker, P.M.M.L. van Krimpen, B.A. van Gratama, J-W. Debets, J.E.M.A.
2005-11-01
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