Chalmers, J.

patient study treatment effect perindopril hypertension treatment bene fit disease progress score receptor analysis polymorphism blood pressure blood pressure europa artery disease treatment effect trial inhibitor association therapy signi pergene reduction ace-inhibitor response population artery table erasmus universiteit rotterdam allele heart fi ndings system pharmacogenetic placebo interaction ace inhibitors body mass index rotterdam ficant value nding result bene fit renin event haplotype enzyme brugt pharmacogenetic score bp response genotype group p-value pathway determinant odds ratio signi ficant blood pressure response variation erasmu europa-trial sample ratio 1.00 agt gene signi ficantly european article research bp reduction simoons ml ace-inhibitor therapy model angiotensinogen william p values