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study statin control association patient abcb 1 disease variant slco 1b dpp 6 effect table result haplotype population index date genome-wide erasmus universiteit rotterdam locus research dpp 6 locus university material nipa 1 interaction cohort region sclerosis response department abcb 1 gene allele index amyotrophic group genome-wide screen genotype genet neurology ischemic heart disease slco 1b gene replication pharmacogenetic duplication transporter rotterdam genetic susceptibility 11.2 netherland pharmacogenomic variability pharmacy records screen deletion participant carrier calcium channel blockers pharmacy polymorphism statin treatment pharmacokinetic als cases als pathogenesis 0.39 record effect size science analysis 0.72 future identi number identi fied simvastatin fication sample neuron illumina radboud university nijmegen
3 Most Recent Publications
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Incomplete segregation of MYH11 variants with thoracic aortic aneurysms and dissections and patent ductus arteriosus
(Article)
Harakalova, M. Smagt, J.J. van der Wessels, M.W. Baars, H.F. Weiss, M.M. Pals, G. Golmard, L. Jeunemaitre, X. Lindhout, D. Cuppen, E. Baas, A.F. Kovel, C.G.F. de Slot, R.V. Poot, M. Nijman, I.J. Medic, J. Joziasse, I.C. Deckers, J.W. Roos-Hesselink, J.W. |
2013-05-01
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A large genome scan for rare CNVs in amyotrophic lateral sclerosis
(Article)
Blauw, H.M. Al-Chalabi, A. Slot, R.V. Strengman, E. Estrada Gil, J.K. Rivadeneira Ramirez, F. Hofman, A. Uitterlinden, A.G. Kiemeney, L.A.L.M. Vermeulen, S.H.H.M. Birve, A. Waibel, S. Andersen, P.M. Meyer, T. Cronin, S. Mclaughlin, R.L. Hardiman, O. Sapp, P.C. Tobin, M.D. Wain, L.V. Tomik, B. Slowik, A. Lemmens, R. Vught, P.W. van Rujescu, D. Schulte, C. Gasser, T. Brown Jr, R.H. Landers, J.E. Robberecht, W. Ludolph, A.C. Ophoff, R.A. Veldink, J.H. Berg, L.H. van den Diekstra, F.P. Es, M.A. van Saris, C.G. Groen, E.J. Rheenen, W. van Koppers, M. |
2010-08-04
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Pharmacogenetic interactions between ABCB1 and SLCO1B1 tagging SNPs and the effectiveness of statins in the prevention of myocardial infarction
(Article)
Peters, B.J.M. Rodin, A.S. Klungel, O.H. Duijn, C.M. van Stricker, B.H.Ch. Slot, R.V. Boer, A. de Maitland-van der Zee, A-H. |
2010-08-01
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