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repair protein locus interaction transcription region globin chromosome substrate expression factor chromatin binding activity nucleotide excision figure strand domain b-globin nucleotide excision repair incision promoter sequence ercc 1-xpf lesion ercc 1 analysis nuclease 1-xpf single-stranded replication fragment tfiih b-globin locus position ercc 1xpf incisions study formation ercci-xpf damage recombination level polymerase endonuclease mouse probe cleavage control genome erythroid replication protein contact group cluster element ssdna patient hoeijmaker 8 c 3/c development liver reaction enhancer organization globin genes product duplex 1997. residue 4 c technology assay nature rna polymerase ii gene expression grosveld yeast antibody x chromosome
10 Most Recent Publications
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Variegated gene expression caused by cell-specific long-range DNA interactions
(Article)
Noordermeer, D. Wit, E. de Klous, P. Werken, H.J.G. van de Simonis, M. Lopez-Jones, M. Eussen, B.H.J. Klein, J.E.M.M. de Singer, R.H. Laat, W.L. de |
2011-08-01
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The inactive X chromosome adopts a unique three-dimensional conformation that is dependent on Xist RNA
(Article)
Splinter, D. Wit, E. de Laat, W.L. de Nora, E.P. Klous, P. Werken, H.J.G. van de Zhu, Y. Kaaij, L.J.T. IJcken, W.F.J. van Gribnau, J.H. Heard, E. |
2011-07-01
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Integrated Transcript and Genome Analyses Reveal NKX2-1 and MEF2C as Potential Oncogenes in T Cell Acute Lymphoblastic Leukemia
(Article)
Homminga, I. Pieters, R. Vlierberghe, P. van Ferrando, A.A. Cayuela, J.M. Verhaaf, B. Beverloo, H.B. Horstmann, M. Haas, V. de Wiekmeijer, A.-S. Pike-Overzet, K. Staal, F.J.T. Langerak, A.W. Laat, W.L. de Soulier, J. Sigaux, F. Meijerink, J.P.P. Rooi, J.J. de Stubbs, A. Verstegen, M.M.A. Vuerhard, M.J. Buijs-Gladdines, J.G.C.A.M. Kooi, C. Klous, P. |
2011-04-12
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High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology
(Article)
Simonis, M. Klous, P. Homminga, I. Galjaard, R-J.H. Rijkers, E.J. Grosveld, F.G. Meijerink, J.P.P. Laat, W.L. de |
2009-10-15
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Joining the loops: β-globin gene regulation
(Article)
Noordermeer, D. Laat, W.L. de |
2008-12-01
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FISH-eyed and genome-wide views on the spatial organisation of gene expression
(Article)
Simonis, M. Laat, W.L. de |
2008-11-01
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Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions
(Article)
Guelen, L. Pagie, L. Steensel, B. van Brasset, E. Meuleman, W. Faza, M.B. Talhout, W. Eussen, B.H.J. Klein, J.E.M.M. de Wessels, L. Laat, W.L. de |
2008-06-12
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Transcription and chromatin organization of a housekeeping gene cluster containing an integrated β-globin locus control region
(Article)
Noordermeer, D. Branco, M.R. Splinter, D. Klous, P. IJcken, W.F.J. van Swagemakers, S.M.A. Koutsourakis, M. Spek, P.J. van der Pombo, A. Laat, W.L. de |
2008-03-01
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Maintenane of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription
(Article)
Palstra, R.J.T.S. Simonis, M. Klous, P. Brasset, E. Eijkelkamp, B. Laat, W.L. de |
2008-02-20
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Three-Dimensional Organization of Gene Expression in Erythroid Cells
(Article)
Laat, W.L. de Klous, P. Kooren, J.A. Noordermeer, D. Palstra, R.J.T.S. Simonis, M. Splinter, D. Grosveld, F.G. |
2008-02-18
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