Singh, V.

protein sample proteomic sclerosis disease peptide analysis biomarker patient pp mscl study spectrometry comparison rr mscl number mass spectrometry vitamin d-binding protein vitamin fication cerebrospinal fl uid proteome cerebrospinal control level difference differentially p-value validation mscl types group technique lesion issue measurement identi research blood experiment brain d-binding table increase reproducibility model application result target proteomics studies sclerosis patients mscl patients biomarker research detection approach process notch / journal development proteome res 2008. interest speci method 2011. 2007. analysis matrix pathology quanti identi fication body fl uid mass spectrometry data cerebrospinal fluid mscl disease types discovery identification apolipoprotein tissue factor csf samples bottleneck future