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scopus: 35410401800

Stumpel, D.J.P.M.

(Dominique Stumpel)


infant methylation expression leukemia patient mll-rearranged mll-rearranged infant sample figure mirna lymphoblastic leukemia dna methylation study cancer lymphoblastic chapter promoter fusion bone marrow samples level translocation treatment marrow blood gene expression island cluster histone zebularine hypermethylation clofarabine group probe mir -196b protein inhibitor microarray mll-af hypermethylated children pattern bone marrow mll translocations -196b microrna dna methylation patterns methylated analysis childhood hdac inhibitors -152 target netherland wild-type mir -152 mll gene den boer ml agent cytarabine research bone marrows profile demethylating table cell lines leukemie methyltransferase pieter hypomethylation result decitabine subtype model promoter hypermethylation element relapse patient samples genen schneider p precursor




5 Most Recent Publications

Epigenetics in MLL-rearranged infant Acute Lymphoblastic Leukemia (Doctoral Thesis)
Stumpel, D.J.P.M.
2012-09-05
Hypermethylation of specific microRNA genes in MLL-rearranged infant acute lymphoblastic leukemia: major matters at a micro scale (Article)
Stumpel, D.J.P.M. Schotte, D. Lange-Turenhout, E.A.M. Schneider, P. Seslija, L. Menezes, R.X. de Marquez, V.E. Pieters, R. Boer, M.L. den Stam, R.W.
2010-11-30
Expression of miR-196b is not exclusively MLL-driven but is especially linked to activation of HOXA genes in pediatric acute lymphoblastic leukemia (Article)
Schotte, D. Lange-Turenhout, E.A.M. Stumpel, D.J.P.M. Stam, R.W. Buijs-Gladdines, J.G.C.A.M.
2010-10-01
Gene expression profiling-based dissection of MLL translocated and MLL germline acute lymphoblastic leukemia in infants (Article)
Stam, R.W. Schneider, P. Hagelstein, J. Linden, M.H. van der Stumpel, D.J.P.M. Menezes, R.X. de Lorenzo, P. de Valsecchi, M.G. Pieters, R.
2010-04-08
Specific promoter methylation identifies different subgroups of MLL-rearranged infant acute lymphoblastic leukemia, influences clinical outcome, and provides therapeutic options (Article)
Stumpel, D.J.P.M. Schneider, P. Roon, E.H.J. van Boer, J.M. Lorenzo, P. de Valsecchi, M.G. Menezes, R.X. de Pieters, R. Stam, R.W.
2009-12-24