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repair protein mhr 23b mouse mhr 23b mice −/− es cells mhr 23b / damage keratinocyte dna damage ddb 2 mhr 23a level nucleotide excision repair embryo excision wild-type analysis development broblast result fi broblasts nucleotide function gg-ner hoeijmaker defect uv-induced dna repair hhr 23b cancer panel ficient genome antibody lesion xeroderma dko cells number mutation xpc-gfp apoptosi pigmentosum xpa −/− synthesis animal abnormality spermatogenesi sugasawa activity sertoli cells expression ubiquitin mhr 23b embryos uv-ddb response uv-ddb activity domain uv irradiation growth exposure tc-ner rad 23 van zeeland weight cerevisiae r e p hxpc-gfp i r 7 ficiency mechanism 14-ddb female sertoli xpc protein hanaoka masutani placenta pathway
5 Most Recent Publications
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Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: Impact on DNA repair and UV-induced skin cancer
(Article)
Pines, A. Backendorf, C.M.P. Alekseev, S. Jansen, J.G. Gruijl, F.R. de Vrieling, H. Mullenders, L.H.F. |
2009-02-01
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Cell-type-specific consequences of nucleotide excision repair deficiencies: Embryonic stem cells versus fibroblasts
(Article)
Waard, H. de Sonneveld, E. Wit, J. de Esveldt-van Lange, R. Hoeijmakers, J.H.J. Vrieling, H. Horst, G.T.J. van der |
2008-10-01
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A novel regulation mechanism of DNA repair by damage-induced and RAD23-dependent stabilization of xeroderma pigmentosum group C protein.
(Article)
Ng, J.M.Y. Vermeulen, W. Horst, G.T.J. van der Bergink, S. Sugasawa, K. Vrieling, H. Hoeijmakers, J.H.J. |
2003-07-01
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Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B
(Article)
Ng, J.M.Y. Vrieling, H. Hoeijmakers, J.H.J. Horst, G.T.J. van der Sugasawa, K. Ooms, M.P. Grootegoed, J.A. Vreeburg, J.T.M. Visser, P. Beems, R.B. Gorgels, T.G.M.F. Hanaoka, F. |
2002-02-05
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Developmental defects and male sterility in mice lacking the ubiquitin-like DNA repair gene mHR23B.
(Article)
Ng, J.M.Y. Vrieling, H. Hoeijmakers, J.H.J. Horst, G.T.J. van der Sugasawa, K. Ooms, M.P. Grootegoed, J.A. Vreeburg, J.T.M. Visser, P. Beems, R.B. Gorgels, T.G.M.F. Hanaoka, F. |
2002-01-01
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