Bono, J.S. de

patient cancer study sample pertuzumab osi -7836 cycle docetaxel infusion -7836 grade phase range tumor minute blood variation treatment level gemcitabine table toxicity schedule fatigue count analysis image cohort activity response tumor cells blood samples metastatic breast cancer cytometry baseline system laboratory result combination pharmacokinetic dose level enumeration plasma number antitumor activity between-laboratory variation breast image interpretation phase i study lymphocyte cytokine classi anti-tumour activity toxicitie subset ctc counts ctc enumeration prostate administration lymphocyte subset analysis dosing 60- minute infusion pertuzumab g attard cytometry part b 100 mg /m control terstappen lw cellsearch system increase research day 1 between-laboratory nucleoside therapy interpretation cellsearch 21 days participant patient samples value