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expression cebpa glucose trypanosome brucei phloretin myeloid protein trypanosoma brucei procyclic culture glycerol trypanosoma differentiation enzyme lineage /eyfp concentration figure analysis level inhibition model c /ebp glycolytic result glycolytic fl ux glucose transport progenitors glycolysi experiment cebpa /eyfp cells hematopoietic growth target progenitor bloodstream control biochem eyfp ϩ transport activity factor transporter pathway lymphoid development blood procyclic forms 100 mm phloretin gene expression change treatment speci stage bloodstream-form population study parasite eyfp ϩ cells transcription thymic glycosome metabolism regulation inhibitor 2- dog erasmus mc cebpacre phloretin treatment glycosomal fication fraction response procyclic culture conditions accumulation colony gly 3p system signi
3 Most Recent Publications
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A domino effect in drug action: From metabolic assault towards parasite differentiation
(Article)
Haanstra, J.R. Kerkhoven, E.J. Westerhoff, H.V. Bakker, B.M. Tuijl, A. van Blits, M. Wurst, M. Nuland, R. van Albert, M-A. Michels, P.A.M. Bouwman, J. Clayton, C. |
2011-01-01
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Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors
(Article)
Wölfler, A. Danen-van Oorschot, A.A. Haanstra, J.R. Valkhof, M. Bodner, C. Vroegindeweij, E.M. Strien, P. van Novak, A. Cupedo, T. Touw, I.P. |
2010-11-18
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Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes
(Article)
Haanstra, J.R. Tuijl, A. van Kessler, P. Reijnders, W. Michels, P.A.M. Westerhoff, H.V. Parsons, M. Bakker, B.M. |
2008-11-18
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