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blood transplantation t cells recovery thymic t-cell thymopoiesi marrow cell transplantation number t cell recovery factor effect hematopoietic allogeneic il -7 murine bone marrow transplantation flt 3l infection thymocyte study reconstitution progenitors immunity immunol sjtrec patient model recipient growth keratinocyte growth factor expansion 4/12/11 ejw.indd thymu animal t-cell recovery lymphoid progenitor thymic function transplant cd 4+cd treg figure disease subset graft chapter cell factor development receptor cytokine donor graft-versus-host disease treatment j exp med j immunol c-kit expression function allogeneic hematopoietic administration lymphoid progenitors transfer graft-versus-host flt 3 ligand cytomegaloviru epithelial month mortality response ligand interleukin result survival bone marrow transplant flt 3l mice control keratinocyte allohsct