Holthausen, J.T.

filament rad 51 recombination protein strand nucleation repair rad 51 filaments dsdna molecule exchange dissociation figure single-stranded dna assembly recombinase lament nucleoprotein concentration structure formation atp hydrolysis strand exchange ssdna disassembly interaction brca 2 binding extension experiment rad 51 fi hydrolysis reaction single-stranded buffer monomer effect study double-stranded dna rad 51 dissociation condition g e effect holliday junctions double-stranded rad 51 monomers control activity junction g e regulation patch mechanism mediator replication presence dna strand exchange dna molecules image rad 51 binding wyman function kanaar dna structures rotterdam length event nucleotide domain holliday helicase van der heijden fluorescence lesion complex replication forks rad 51 filament rad 51 nucleation nucleation rate fl ow cell introduction cancer