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kinase activity expression protein vegfr analysis phosphorylation idh 1r pathway figure embryo result mutation tumour glioma pneumonia study mm cells tumor substrate kinome notch idh 1 factor d-asb astrocytoma pilocytic 11cul growth proliferation patient cancer kinase activity idh 1r cells level cullin response infection mm pc receptor asb 11cul embryos activation idh 1wt myeloma 87 cells idh 1 mutations vegfr -2 0.0 pneumococcal zebrafish cell lines d-asb 11 pneumococcal pneumonia antibody signal control phosphorylated -2-hg asb 11cul idh 2 mutations 7 9 8 7 9 0 peptide l m e cullin box domain pilocytic astrocytoma profile sample endothelium pneumoniae volume tissue deltaa paediatric pilocytic astrocytoma survival target presence socs-box array
6 Most Recent Publications
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Major remodelling of the murine stem cell kinome following differentiation in the hematopoietic compartment
(Article)
Hazen, A.L. Diks, S.H. Wahle, J.A. Fuhler, G.M. Peppelenbosch, M.P. Kerr, W.G. |
2011-08-05
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Vascular endothelial growth factor receptor 2 (VEGFR-2) signalling activity in paediatric pilocytic astrocytoma is restricted to tumour endothelial cells
(Article)
Sikkema, A.H. Bont, E.S.J.M. de Molema, G. Dimberg, A. Zwiers, P.J. Diks, S.H. Hoving, E.W. Kamps, W.A. Peppelenbosch, M.P. Dunnen, W.F.A. den |
2011-08-01
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Widespread deregulation of phosphorylation-based signaling pathways in multiple myeloma cells:Opportunities for therapeutic intervention
(Article)
Fuhler, G.M. Diks, S.H. Peppelenbosch, M.P. Kerr, W.G. |
2011-07-01
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Kinase activity profiling of pneumococcal pneumonia
(Article)
Hoogendijk, A.J. Diks, S.H. Poll, T. van der Peppelenbosch, M.P. Wieland, C.W. |
2011-04-11
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IDH1 R132H decreases proliferation of glioma cell lines in vitro and in vivo
(Article)
Bralten, L.B.C. Kloosterhof, N.K. Struys, E. Jakobs, C. Salomons, G.S. Diks, S.H. Peppelenbosch, M.P. Kremer, A. Hoogenraad, C.C. Sillevis Smitt, P.A.E. French, P.J. Balvers, R. Sacchetti, A. Lapre, L. Lamfers, M.L.M. Leenstra, S. Jonge, H. de Kros, J.M. Jansen, E.E.W. |
2011-03-01
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Essential role for the d-asb11 cul5 box domain for proper notch signaling and neural cell fate decisions in Vivo
(Article)
Silva, M.A.S. Tee, J-M. Paridaen, J. Brouwers, A. Runtuwene, V. Zivkovic, D. Diks, S.H. Guardavaccaro, D. Peppelenbosch, M.P. |
2010-12-03
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