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protein fusion assay leukemia patient immunobead bcr-abl antibody detection fusion proteins sample immunobead assay bcr –abl transcript protease breakpoint result cell lines value cytometric figure myeloid mfi values blood inhibitor lysate m-bcr myeloid leukemia chromosome fusion protein aberration technique bcr-abl immunobead assay 4 1 c bcr gene speci euroflow myeloid cells bcr –abl protein fusion gene transcripts cell lysates sensitivity lymphoblastic leukemia pml-rara region level disease cancer bd biosciences euroflow consortium bcp-all leukemic cells department bcr –abl proteins experiment fl ow cytometer erasmus mc signal research laboratory room temperature precursor-b-all variant bcr –abl transcripts fl ow cytometry dekking uorescence tyrosine method multiplex k 562 cml cells patient samples membrane 10 min protease inhibitors pretreatment bcr-abl fusion proteins fl uorescence intensity fi lter plate
2 Most Recent Publications
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Detection of fusion genes at the protein level in leukemia patients via the flow cytometric immunobead assay
(Article)
Dekking, E. Velden, V.H.J. van der Kalina, T. Kovac, M. Evans, P. Hoogeveen, P.G. Flores-Montero Orfao, A. Comans-Bitter, W.M. Staal, F.J.T. Dongen, J.J.M. van Böttcher, S. Brüggemann, M. Sonneveld, E. Koning-Goedheer, A. Boeckx, N. Lucio, P. Sedek, L. Szczepański, T. |
2010-09-01
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Flow cytometric immunobead assay for the detection of BCR-ABL fusion proteins in leukemia patients
(Article)
Weerkamp, F. Dekking, E. Poecke, N. van Lucio, P. Mendonça, A. Sedek, L. Szczepański, T. Kalina, T. Kovac, M. Hoogeveen, P.G. Flores-Montero Orfao, A. Ng, Y.Y. Macintyre, E. Lhermitte, L. Chen, R. Brouwer-De Cock, K.A.J. Linden, A. van der Noordijk, A.L. Comans-Bitter, W.M. Staal, F.J.T. Dongen, J.J.M. van Velden, V.H.J. van der Wai, H. Böttcher, S. Brüggemann, M. Sluijs, A.J. van der Koning, A. Boeckx, N. |
2009-04-24
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