Essioux, L.

impdh patient impdh activity activity polymorphism marker value protein study variant monophosphate dehydrogenase sample table group transplant inosine wild-type association region transplantation schizophrenia genotype c polymorphism allele effect concentration variant carrier group pnas web site inosine monophosphate dehydrogenase mycophenolate mofetil mycophenolic acid transplant patients result sequence mycophenolate impdh type ii analysis mycophenolic aucact interaction frequency curve p values control therapy aucmpa plg 72 impdh type i mofetil haplotype p value method genomic carrier blood level chromosome allele frequency disease pharmacogenetic 5- mb region difference time –effect curve plasma brain pharmacodynamic psychiatry correlation linkage disequilibrium 80 patients translation hambach p canadian mdaao product glander day 6 posttransplantation netherland rejection