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sunitinib patient cancer polymorphism hypertension treatment factor study sunitinib treatment analysis haplotype survival grade 3 hypertension metastatic therapy association multivariate blood center presence cell carcinoma abcb 1 haplotype tumor vegfr grade pressure outcome number cycle level pharmacokinetic carcinoma mrcc patients cell cancer disease change cyp 3a mskcc oncol tcg copy department research baseline progression-free survival metastatic sites group characteristic analyses vegfa month mskcc risk factors vegfr -2 netherland article cancer research treatment cycle diastolic blood pressure result acg haplotype nr 1i haplotype pharmacodynamic transporter blood pressure table abcb 1 university multivariate analyses exposure prognostic systolic blood pressure criteria cyp 3a 6986 a-allele prognostic criteria cat copy abcg 2 sunitinib therapy growth oncology onlinefirst
3 Most Recent Publications
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Polymorphisms in endothelial nitric oxide synthase (eNOS) and vascular endothelial growth factor (VEGF) predict sunitinib-induced hypertension
(Article)
Eechoute, K. Veldt, A.A.M. van der Mathijssen, R.H.J. Boven, E. Oosting, R.S. Kappers, M.H.W. Wessels, J.A.M. Gelderblom, H. Guchelaar, H.J. Reyners, A.K.L. Herpen, C.M.L. Haanen, J.B. |
2012-10-01
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Genetic polymorphisms associated with a prolonged progression-free survival in patients with metastatic renal cell cancer treated with sunitinib
(Article)
Veldt, A.A.M. van der Eechoute, K. Gelderblom, A.J. Gietema, J.A. Guchelaar, H.J. Erp, N.P. van Eertwegh, A.J.M. van den Haanen, J.B. Mathijssen, R.H.J. Wessels, J.A.M. |
2011-02-01
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Myelosuppression by sunitinib is flt-3 genotype dependent
(Article)
Erp, N.P. van Mathijssen, R.H.J. Veldt, A.A.M. van der Haanen, J.B. Reyners, A.K.L. Eechoute, K. Boven, E. Wessels, J.A.M. Guchelaar, H.J. Gelderblom, H. |
2010-08-01
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