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expression gata 3 2-gata gata -2 / thymocyte cd 2-gata development level number sp 3 / dp cells factor embryo gata 3 expression figure lineage gata -2 analysis hematopoietic lymphoma result wild-type transcription c-myc stage hsc activity activity recipient t cell development notch selection mouse thymu differentiation erythroid t-cell blood liver protein cd 5 expression cd 5 levels thymic adult defect explant tissue 11.10 transplantation cd 2-gata mice notch 1 control cd 2-gata transgene surface liver cells isp cells value flow cytometric analysis gata -2 dose increase c-myc expression cycle spleen population ficient immunol deletion t cells repopulation knockout dp stage reduction percentage region transgene erasmus mc rotterdam progression ctcf-de figure 6 assay ab t cells
5 Most Recent Publications
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CTCF regulates cell cycle progression of αβ T cells in the thymus
(Article)
Heath, H. Ribeiro de Almeida, C. Hendriks, R.W. Galjart, N.J. Sleutels, F. Dingjan, G.M. Nobelen, S. van de Jonkers, I.H. Ling, K-W. Gribnau, J.H. Renkawitz, R. Grosveld, F.G. |
2008-11-05
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Cooperation of Gata3, c-Myc and Notch in malignant transformation of double positive thymocytes
(Article)
Hamburg, J.P. van Bruijn, M.J.W. de Dingjan, G.M. Beverloo, H.B. Diepstraten, H.J.A. Ling, K-W. Hendriks, R.W. |
2008-06-01
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GATA3 controls the expression of CD5 and the T cell receptor during CD4 T cell lineage development
(Article)
Ling, K-W. Hamburg, J.P. van Bruijn, M.J.W. de Kurek, D.M. Dingjan, G.M. Hendriks, R.W. |
2007-04-01
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GATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cells
(Article)
Ling, K-W. Ottersbach, K. Hamburg, J.P. van Oziemlak, A. Tsai, F.Y. Orkin, S.H. Ploemacher, R.E. Hendriks, R.W. Dzierzak, E.A. |
2004-01-01
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Impaired hematopoiesis in mice lacking the transcription factor Sp3
(Article)
Loo, P.F. van Bouwman, P. Ling, K-W. Middendorp, S. Suske, G. Grosveld, F.G. Dzierzak, E.A. Philipsen, J.N.J. Hendriks, R.W. |
2003-01-01
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