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study osteoarthritis knee oa association control hip oa university finition radiographic phenotype rheum cohort research result analysis hand oa table effect arthritis finite allele haplotype osteophyte knee osteoarthritis rotterdam population grade meta-analysi diagnosis department cartilage heterogeneity subject polymorphism netherland kerkhof evidence consortium genome-wide score rotterdam study recommendation summary meulenbelt k /l score oa phenotypes criteria rs 7775 gdf 5 analyses center valde osteoporotic fractures hospital model variant patient genetic finite osteophyte factor women medicine / osteoarthritis method random-effect health number sample knee pain symptom caucasian finite osteophytes disease spector rs 288326 prevalence joint hip roa risk factors severity
6 Most Recent Publications
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Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
(Article)
Panoutsopoulou, K. Southam, L. Deloukas, P. Doherty, M. McCaskie, A. Ollier, W.E.R. Ralston, S.H. Spector, T.D. Valdes, A.M. Wallis, G.A. Wilkinson, J.M. Battley, K. Elliott, K.S. Blackburn, H. Blanco, F.J. Bumpstead, S. Cupples, L.A. Day-Williams, A.G. Dixon, K. Esko, T. Evangelou, E. Felson, D. Gómez-Reino, J.J. Wrayner, N. Gonzalez, A. Gordon, A. Gwilliam, R. Halldorsson, B.V. Hauksson, V.B. Hofman, B. Hunt, S.E. Ioannidis, J.P.A. Ingvarsson, T. Jonsdottir, I. Zhai, G. Jonsson, H. Keen, R. Kerkhof, H.J.M. Kloppenburg, M. Koller, N. Lakenberg, N. Lane, N.E. Lee, A.T. Metspalu, A. Meulenbelt, I. Beazley, C. Nevitt, M.C. O'Neill, F. Parimi, N. Potter, S.C. Rego-Perez, I. Riancho, J.A. Sherburn, K. Slagboom, P.E. Stefansson, K. Styrkarsdottir, U. Thorleifsson, G. Sumillera, M. Swift, D. Thorsteinsdottir, U. Tsezou, A. Uitterlinden, A.G. Meurs, J.B.J. van Watkins, B. Wheeler, M. Mitchell, S. Zhu, Y. Arden, N.K. Zmuda, J.M. Zeggini, E. Loughlin, J. Carr, A.M. Chapman, K. |
2011-05-01
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Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis
(Article)
Kerkhof, H.J.M. Doherty, M. Hart, D.J. Hofman, A. Javaid, K. Kerna, I. Kisand, K. Kloppenburg, M. Krasnokutsky, S. Maciewicz, R.A. Meulenbelt, I. Muir, K.R. Arden, N.K. Rivadeneira Ramirez, F. Samuels, J. Sezgin, M. Slagboom, E.P. Smith, A.J.P. Spector, T.D. Tamm, A. Uitterlinden, A.G. Wheeler, M. Zhai, G. Abramson, S.B. Zhang, W. Meurs, J.B.J. van Valdes, A.M. Attur, M. Bos, S.D. Cooper, C. Dennison, E.M. Doherty, S.A. Evangelou, E. |
2011-03-01
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Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: The TREAT-OA consortium
(Article)
Kerkhof, H.J.M. Meulenbelt, I. Doherty, S.A. Felson, D. Gonzalez, A. Gordon, A. Harilainen, A. Hart, D.J. Hauksson, V.B. Heliovaara, M. Hofman, A. Ikegawa, S. Akune, T. Ingvarsson, T. Jiang, Q. Jonsson, H. Jonsdottir, I. Kawaguchi, H. Kloppenburg, M. Kujala, U.M. Lane, N.E. Leino-Arjas, P. Lohmander, L.S. Arden, N.K. Luyten, F.P. Malizos, K.N. Nakajima, M. Nevitt, M.C. Pols, H.A.P. Rivadeneira Ramirez, F. Shi, D. Slagboom, E. Spector, T.D. Stefansson, K. Aromaa, A. Sudo, A. Tamm, A. Tamm, A.E. Tsezou, A. Uchida, A. Uitterlinden, A.G. Wilkinson, J.M. Yoshimura, N. Valdes, A.M. Meurs, J.B.J. van Bierma-Zeinstra, S.M.A. Carr, A.M. Cooper, C. Dai, J. Doherty, M. |
2011-03-01
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EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis
(Article)
Zhang, W. Doherty, M. Mazières, B. Pavelka, K. Punzi, L. So, A.K. Tuncer, T. Watt, I. Bijlsma, J.W.J. Peat, G. Bierma-Zeinstra, S.M.A. Arden, N.K. Bresnihan, B. Herrero-Beaumont, G. Kirschner, S. Leeb, B.F. Lohmander, L.S. |
2010-03-01
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A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22
(Article)
Kerkhof, H.J.M. Lories, R.J. Thorleifsson, G. Zhai, G. Zhang, F. Zhu, Y. Breggen, R. van der Carr, A.M. Doherty, M. Felson, D. Gonzalez, A. Halldorsson, B.V. Meulenbelt, I. Hart, D.J. Hauksson, V.B. Hofman, A. Ioannidis, J.P.A. Kloppenburg, M. Lane, N.E. Loughlin, J. Luyten, F.P. Nevitt, M.C. Parimi, N. Jonsdottir, I. Pols, H.A.P. Rivadeneira Ramirez, F. Slagboom, E. Styrkarsdottir, U. Tsezou, A. Putte, T. van de Zmuda, J. Spector, T.D. Zwart, J-A. Uitterlinden, A.G. Valdes, A.M. Meurs, J.B.J. van Arp, P.P. Ingvarsson, T. Jhamai, M. Jonsson, H. Stolk, L. |
2010-02-01
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Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand
(Article)
Evangelou, E. Chapman, K. Hauksson, V.B. Hofman, A. Hart, D.J. Ikegawa, S. Ingvarsson, T. Jiang, Q. Jonsdottir, I. Jonsson, H. Kerkhof, H.J.M. Kloppenburg, M. Meulenbelt, I. Lane, N.E. Li, J. Lories, R.J. Meurs, J.B.J. van Näkki, A. Nevitt, M.C. Rodriguez-Lopez, J. Shi, D. Slagboom, P.E. Zwart, J-A. Karassa, F.B. Tsezou, A. Wallis, G.A. Watson, C.M. Spector, T.D. Uitterlinden, A.G. Valdes, A.M. Ioannidis, J.P.A. Loughlin, J. Carr, A.M. Doherty, M. Gómez-Reino, J.J. Gonzalez, A. Halldorsson, B.V. |
2009-06-01
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