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study osteoarthritis association knee oa cohort research university finition control department rheum vitamin variant 25- hydroxyvitamin osteophyte radiographic hip oa result sample knee osteoarthritis health rotterdam finite institute genome-wide medicine polymorphism 25- score arthritis hospital diagnosis hydroxyvitamin phenotype table consortium netherland concentration meta-analysi allele valde effect number disease recommendation twinsuk haplotype evidence genotype kerkhof k /l score center cartilage article analysis centre trust factor caucasian patient signi replication finite osteophyte epidemiology meulenbelt i value subject population oxford / osteoarthritis spector finite osteophytes variation knee pain symptom region signal grant prevalence hip roa
8 Most Recent Publications
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A variant in MCF2L is associated with osteoarthritis
(Article)
Day-Williams, A.G. Southam, L. Keis, A. Kerkhof, H.J.M. Thorleifsson, G. Arden, N.K. Carr, A. Chapman, K. Deloukas, P. Loughlin, J. McCaskie, A. Ollier, W.E.R. Panoutsopoulou, K. Ralston, S.H. Spector, T.D. Wallis, G.A. Wilkinson, J.M. Aslam, N. Birell, F. Carluke, I. Joseph, J. Rai, A. Reed, M. Rayner, N.W. Walker, K. Doherty, S.A. Jonsdottir, I. Maciewicz, R.A. Muir, K.R. Metspalu, A. Rivadeneira Ramirez, F. Stefansson, K. Styrkarsdottir, U. Uitterlinden, A.G. Esko, T. Meurs, J.B.J. van Zhang, W. Valdes, A.M. Zeggini, E. Estrada Gil, J.K. Helgadottir, H.T. Hofman, A. Ingvarsson, T. Jonsson, H. |
2011-09-09
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The GDF5 rs143383 polymorphism is associated with osteoarthritis of the knee with genome-wide statistical significance
(Article)
Valdes, A.M. Evangelou, E. Cooper, C. Dennison, E.M. Zhang, W. Muir, K.R. Ioannidis, J.P.A. Wheeler, M. Maciewicz, R.A. Meurs, J.B.J. van Arden, N.K. Spector, T.D. Kerkhof, H.J.M. Tamm, A.E. Doherty, S.A. Kisand, K. Kerna, I. Uitterlinden, A.G. Hofman, A. Rivadeneira Ramirez, F. |
2011-05-01
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Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
(Article)
Panoutsopoulou, K. Southam, L. Deloukas, P. Doherty, M. McCaskie, A. Ollier, W.E.R. Ralston, S.H. Spector, T.D. Valdes, A.M. Wallis, G.A. Wilkinson, J.M. Battley, K. Elliott, K.S. Blackburn, H. Blanco, F.J. Bumpstead, S. Cupples, L.A. Day-Williams, A.G. Dixon, K. Esko, T. Evangelou, E. Felson, D. Gómez-Reino, J.J. Wrayner, N. Gonzalez, A. Gordon, A. Gwilliam, R. Halldorsson, B.V. Hauksson, V.B. Hofman, B. Hunt, S.E. Ioannidis, J.P.A. Ingvarsson, T. Jonsdottir, I. Zhai, G. Jonsson, H. Keen, R. Kerkhof, H.J.M. Kloppenburg, M. Koller, N. Lakenberg, N. Lane, N.E. Lee, A.T. Metspalu, A. Meulenbelt, I. Beazley, C. Nevitt, M.C. O'Neill, F. Parimi, N. Potter, S.C. Rego-Perez, I. Riancho, J.A. Sherburn, K. Slagboom, P.E. Stefansson, K. Styrkarsdottir, U. Thorleifsson, G. Sumillera, M. Swift, D. Thorsteinsdottir, U. Tsezou, A. Uitterlinden, A.G. Meurs, J.B.J. van Watkins, B. Wheeler, M. Mitchell, S. Zhu, Y. Arden, N.K. Zmuda, J.M. Zeggini, E. Loughlin, J. Carr, A.M. Chapman, K. |
2011-05-01
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Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis
(Article)
Kerkhof, H.J.M. Doherty, M. Hart, D.J. Hofman, A. Javaid, K. Kerna, I. Kisand, K. Kloppenburg, M. Krasnokutsky, S. Maciewicz, R.A. Meulenbelt, I. Muir, K.R. Arden, N.K. Rivadeneira Ramirez, F. Samuels, J. Sezgin, M. Slagboom, E.P. Smith, A.J.P. Spector, T.D. Tamm, A. Uitterlinden, A.G. Wheeler, M. Zhai, G. Abramson, S.B. Zhang, W. Meurs, J.B.J. van Valdes, A.M. Attur, M. Bos, S.D. Cooper, C. Dennison, E.M. Doherty, S.A. Evangelou, E. |
2011-03-01
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Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: The TREAT-OA consortium
(Article)
Kerkhof, H.J.M. Meulenbelt, I. Doherty, S.A. Felson, D. Gonzalez, A. Gordon, A. Harilainen, A. Hart, D.J. Hauksson, V.B. Heliovaara, M. Hofman, A. Ikegawa, S. Akune, T. Ingvarsson, T. Jiang, Q. Jonsson, H. Jonsdottir, I. Kawaguchi, H. Kloppenburg, M. Kujala, U.M. Lane, N.E. Leino-Arjas, P. Lohmander, L.S. Arden, N.K. Luyten, F.P. Malizos, K.N. Nakajima, M. Nevitt, M.C. Pols, H.A.P. Rivadeneira Ramirez, F. Shi, D. Slagboom, E. Spector, T.D. Stefansson, K. Aromaa, A. Sudo, A. Tamm, A. Tamm, A.E. Tsezou, A. Uchida, A. Uitterlinden, A.G. Wilkinson, J.M. Yoshimura, N. Valdes, A.M. Meurs, J.B.J. van Bierma-Zeinstra, S.M.A. Carr, A.M. Cooper, C. Dai, J. Doherty, M. |
2011-03-01
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GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women
(Article)
Williams, F.M.K. Popham, M. Valdes, A.M. Meurs, J.B.J. van Hart, D.J. Schepper, E.I.T. de Bierma-Zeinstra, S.M.A. Hofman, B. Uitterlinden, A.G. Arden, N.K. Cooper, C. Spector, T.D. |
2011-03-01
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Common genetic determinants of vitamin D insufficiency: A genome-wide association study
(Article)
Wang, T.J. Zhang, F. Peltonen, L. Cooper, C. O'Reilly, P.F. Houston, D.K. Glazer, N.L. Vandenput, L. Peacock, M. Shi, J. Rivadeneira Ramirez, F. McCarthy, M.I. Richards, J.B. Anneli, P. Boer, I.H. de Mangino, M. Kato, B. Smyth, D.J. Booth, S.L. Jacques, P.F. Burke, G.L. Goodarzi, M. Cheung, C.L. Kestenbaum, B. Wolf, M. Rice, K. Goltzman, D. Hidiroglou, N. Ladouceur, M. Wareham, N.J. Hocking, L.J. Hart, D.J. Arden, N.K. Malik, S. Meurs, J.B.J. van Fraser, W.D. Hartikainen, A.L. Zhai, G. Macdonald, H.M. Forouhi, N.G. Loos, R.J.F. Reid, D.M. Hakim, A. Dennison, E.M. Liu, Y. Berry, D. Power, C. Stevens, H.E. Jaana, L. Vasan, R.S. Soranzo, N. Bojunga, J. Psaty, B.M. Lorentzon, M. Foroud, T. Harris, T.B. Kiel, D.P. Hofman, A. Jansson, J.O. Cauley, J.A. Uitterlinden, A.G. Gibson, Q. Jarvelin, M.R. Karasik, D. Siscovick, D.S. Econs, M.J. Kritchevsky, S.B. Streeten, E.A. Florez, J.C. Todd, J.A. Dupuis, J. Hyppönen, E. Spector, T.D. Ohlsson, C. Koller, D.L. |
2010-06-10
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EULAR evidence-based recommendations for the diagnosis of knee osteoarthritis
(Article)
Zhang, W. Doherty, M. Mazières, B. Pavelka, K. Punzi, L. So, A.K. Tuncer, T. Watt, I. Bijlsma, J.W.J. Peat, G. Bierma-Zeinstra, S.M.A. Arden, N.K. Bresnihan, B. Herrero-Beaumont, G. Kirschner, S. Leeb, B.F. Lohmander, L.S. |
2010-03-01
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