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study association cohort osteoarthritis bone mineral density rotterdam allele hip oa knee oa finition rotterdam study fracture density osteophyte mineral polymorphism research chingford k /l score finite variant score chingford study phenotype table twinsuk control result hand oa radiographic rheum cartilage women arthritis sample meta-analysi university subject kerkhof replication analysis haplotype power number spector disease lrp 5 effect osteoporotic consortium valde department spine osteoporosis genome-wide risk alleles protein genotype population variation finite osteophyte netherland osteoporotic fractures signi spector td / osteoarthritis femoral neck heterogeneity female finite osteophytes genome-wide association study value caucasian 324gly knee osteoarthritis hip roa grade osteoporotic fracture e ffect severity
6 Most Recent Publications
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Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis
(Article)
Kerkhof, H.J.M. Doherty, M. Hart, D.J. Hofman, A. Javaid, K. Kerna, I. Kisand, K. Kloppenburg, M. Krasnokutsky, S. Maciewicz, R.A. Meulenbelt, I. Muir, K.R. Arden, N.K. Rivadeneira Ramirez, F. Samuels, J. Sezgin, M. Slagboom, E.P. Smith, A.J.P. Spector, T.D. Tamm, A. Uitterlinden, A.G. Wheeler, M. Zhai, G. Abramson, S.B. Zhang, W. Meurs, J.B.J. van Valdes, A.M. Attur, M. Bos, S.D. Cooper, C. Dennison, E.M. Doherty, S.A. Evangelou, E. |
2011-03-01
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Recommendations for standardization and phenotype definitions in genetic studies of osteoarthritis: The TREAT-OA consortium
(Article)
Kerkhof, H.J.M. Meulenbelt, I. Doherty, S.A. Felson, D. Gonzalez, A. Gordon, A. Harilainen, A. Hart, D.J. Hauksson, V.B. Heliovaara, M. Hofman, A. Ikegawa, S. Akune, T. Ingvarsson, T. Jiang, Q. Jonsson, H. Jonsdottir, I. Kawaguchi, H. Kloppenburg, M. Kujala, U.M. Lane, N.E. Leino-Arjas, P. Lohmander, L.S. Arden, N.K. Luyten, F.P. Malizos, K.N. Nakajima, M. Nevitt, M.C. Pols, H.A.P. Rivadeneira Ramirez, F. Shi, D. Slagboom, E. Spector, T.D. Stefansson, K. Aromaa, A. Sudo, A. Tamm, A. Tamm, A.E. Tsezou, A. Uchida, A. Uitterlinden, A.G. Wilkinson, J.M. Yoshimura, N. Valdes, A.M. Meurs, J.B.J. van Bierma-Zeinstra, S.M.A. Carr, A.M. Cooper, C. Dai, J. Doherty, M. |
2011-03-01
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GDF5 single-nucleotide polymorphism rs143383 is associated with lumbar disc degeneration in Northern European women
(Article)
Williams, F.M.K. Popham, M. Valdes, A.M. Meurs, J.B.J. van Hart, D.J. Schepper, E.I.T. de Bierma-Zeinstra, S.M.A. Hofman, B. Uitterlinden, A.G. Arden, N.K. Cooper, C. Spector, T.D. |
2011-03-01
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A genome-wide association study suggests that a locus within the ataxin 2 binding protein 1 gene is associated with hand osteoarthritis: The Treat-OA consortium
(Article)
Zhai, G. Meurs, J.B.J. van Williams, F.M.K. Inouye, M. Kloppenburg, M. Demissie, S Slagboom, E. Uitterlinden, A.G. Spector, T.D. Livshits, G. Meulenbelt, I. Valdes, A.M. Soranzo, N. Hart, D.J. Zhang, F. Kato, B.S. Richards, J.B. |
2009-09-01
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Radiographic osteoarthritis at three joint sites and FRZB, LRP5, and LRP6 polymorphisms in two population-based cohorts
(Article)
Kerkhof, J.M. Uitterlinden, A.G. Meurs, J.B.J. van Valdes, A.M. Hart, D.J. Rivadeneira Ramirez, F. Jhamai, M. Hofman, A. Pols, H.A.P. Bierma-Zeinstra, S.M.A. Spector, T.D. |
2008-10-01
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Bone mineral density, osteoporosis, and osteoporotic fractures: a genome-wide association study
(Article)
Richards, J.B. Rivadeneira Ramirez, F. Valdes, A.M. Arp, P.P. Whittaker, P. Verlaan, D.J. Jhamai, M. Kumanduri, V. Moorhouse, M.J. Meurs, J.B.J. van Hofman, A. Pols, H.A.P. Inouye, M. Hart, D.J. Zhai, G. Kato, B.S. Mullin, B. Zhang, F. Deloukas, P. Uitterlinden, A.G. Spector, T.D. Pastinen, T. Soranzo, N. Wilson, S.G. Andrew, T. Falchi, M. Gwilliam, R. Ahmadi, K.R. |
2008-03-09
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