Wheeler, M.

study knee oa hip oa osteoarthritis haplotype association control severity meta-analysi netherland genotype interleukin knee osteoarthritis effect region c-t-a haplotype radiographic polymorphism variation cohort c-t-a k /l 1 kerkhof rs 419598 department table research university signi twinsuk cartilage allele garp study sample heterogeneity number / osteoarthritis k /l 3 rotterdam random-effect meulenbelt valde novel data analysis evidence radiographic severity hjm kerkhof rheum medicine result frequency doherty il 1b c-g-c article power smith haplotype frequencies spector td arthritis attur estonia signi ficantly h.j.m random-effects model sample size range case-control population nottingham model center author summary women addition method subject ficant spector