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activation intestine 407 cells kinase increase intestine efflux hypotonic channel release anion membrane protein medium extracellular extracellular atp figure hypotonicity-induced result stimulation erk-l endocytosi response control physiol addition activity exocytosi 5 min regulation concentration hypo-osmotic inhibition erk-l /2 effect surface -1\erk table cell types tilly swelling-induced receptor phosphorylation current volume inhibitor potentiation apyrase atp release chapter pathway rvd response buffer study osmosensitive -1/2 jonge purinoceptor cytochalasin treatment condition intracellular mechanism volume-sensitive cytochalasin b pretreatment image conductance uptake hypotonic stimulation hypo-osmotic stimulation expression suramin erk -1\erk activation ptdins 3- kinase cytoskeleton stress tyrosine experiment erk -1\erk force
4 Most Recent Publications
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Increased vesicle recycling in response to osmotic cell swelling. Cause and consequence of hypotonicity-provoked ATP release.
(Article)
Wijk, Th. van der Tomassen, S.F.B. Houtsmuller, A.B. Jonge, H.R. de Tilly, B.C. |
2003-10-10
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Signal Transduction Involved in Cell Volume Regulation
(Doctoral Thesis)
Wijk, Th. van der |
2001-01-24
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Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels
(Article)
Wijk, Th. van der Jonge, H.R. de Tilly, B.C. |
1999-01-01
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Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in intestine 407 cells involves the Ras/Raf-signalling pathway
(Article)
Wijk, Th. van der Dorrestijn, J. Narumiya, S. Maassen, J.A. Jonge, H.R. de Tilly, B.C. |
1998-01-01
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