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cancer mutation carcinoma analysis colorectal sample methylation probe adenoma fraction study colorectal cancer patient hct 116 cells carrier promoter tumor expression mutyh methylated colon aberration number lovastatin adenomas ptprgint table tumour statin control msh 6 netherland tissue result region crc risk chromosomal tumours crc cells protein rectal biopsy bmp 2 promoter carcinoma fraction island 165cy event figure adenoma fractions bmp 2 ptprgint 1 methylation chromosomal aberrations dna methylation germline effect treatment ptprg allele genet association differentiation binding adenoma fraction identi carcinoma fractions leiden phenotype identi fied genomic ctcf binding unmethylated tyr 165cys heterogeneity chromosome ratio 2 mm lovastatin variant ptprgint 1 reference probes pathway
6 Most Recent Publications
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Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway
(Article)
Kodach, L.L. Jacobs, R.J. Hardwick, J.C.H. Voorneveld, P.W. Wildenberg, M.E. Verspaget, H.W. Wezel, T. van Morreau, H. Hommes, D.W. Peppelenbosch, M.P. Brink, G.R. van den |
2011-11-01
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Tumour-specific methylation of PTPRG intron 1 locus in sporadic and Lynch syndrome colorectal cancer
(Article)
Roon, E.H.J. van Miranda, N.F.C.C. de Nieuwenhuizen, M.P. Meijer, E.J. de Puijenbroek, M. van Yan, P.S. Huang, T.H.M. Wezel, T. van Morreau, H. Boer, J.M. |
2011-03-01
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MLPAinter for MLPA interpretation: An integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification
(Article)
Eijk, R. van Eilers, P.H. Natté, R. Cleton-Jansen, A. Morreau, H. Wezel, T. van Oosting, J. |
2010-01-29
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Chromosome 8q23.3 and 11q23.1 Variants Modify Colorectal Cancer Risk in Lynch Syndrome
(Article)
Wijnen, J.T. Brohet, R.M. Hoogerbrugge, N. Menko, F. Os, T.A.M. van Sijmons, R.H. Verhoef, S. Wagner, A. Nagengast, F.M. Kleibeuker, J.H. Devilee, P. Morreau, H. Eijk, R. van Goldgar, D. Tomlinson, I.P. Houlston, R. Wezel, T. van Vasen, H. Jagmohan-Changur, S. Middeldorp, A. Tops, C. Puijenbroek, M. van Ausems, M.G.E.M. Gómez García, E.B. Hes, F.J. |
2009-01-01
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Progression and tumor heterogeneity analysis in early rectal cancer
(Article)
Lips, E.H. Eijk, R. van Morreau, H. Graaf, E.J.R. de Doornebosch, P. Miranda, N.F.C.C. de Oosting, J. Karsten, T.M. Eilers, P.H. Tollenaar, R.A.E.M. Wezel, T. van |
2008-02-01
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The natural history of a combined defect in MSH6 and MUTYH in a HNPCC family
(Article)
Puijenbroek, M. van Nielsen, M. Hes, F.J. Morreau, H. Reinards, T.H.C.M. Weiss, M.M. Wagner, A. Hendriks, Y. Vasen, H. Tops, C. Wijnen, J.T. Wezel, T. van |
2007-03-01
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