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Tilly, B.C.

(Bernard Tilly)


activation channel intestine 407 cells efflux cgk ii kinase protein release physiol blood cells membrane cgk i chloride anion iec-cf 7 cells increase intestine medium conductance hypotonic result pathway blood volume control regulation phosphorylation taurine jonge response addition 125 i efflux activity iec-cf -1\erk inhibitor osmolyte culture study hypotonicity-induced stimulation endocytosi extracellular atp cholesterol tyrosine extracellular 508delcftr epithelial chloride conductance expression tilly experiment inhibition current erasmus mc effect swelling-induced table treatment van der wijk 5 min plasma membrane fibrosis genistein f 508delcftr figure erk -1\erk activation model epithelial cells fibroblast patch concentration cftr cl channels erk -1\erk condition forskolin solution cell volume intracellular erasmu




10 Most Recent Publications

Osmosignaling and Volume Regulation in Intestinal Epithelial Cells (Article)
Lim, C.H. Bot, A.G. Jonge, H.R. de Tilly, B.C.
2007-12-01
Cholesterol depletion and genistein as tools to promote F508delCFTR retention at the plasma membrane (Article)
Lim, C.H. Bijvelds, M.J. Nigg, A.L. Schoonderwoerd, K. Houtsmuller, A.B. Jonge, H.R. de Tilly, B.C.
2007-09-05
Osmotic swelling-provoked release of organic osmolytes in human intestinal epithelial cells. (Article)
Tomassen, S.F.B. Fekkes, D. Jonge, H.R. de Tilly, B.C.
2004-06-01
Plasmodium falciparum-activated chloride channels are defective in erythrocytes from cystic fibrosis patients. (Article)
Verloo, P. Kocken, C.H. Wel, A. van der Tilly, B.C. Hogema, B.M. Sinaasappel, M. Thomas, A.W. Jonge, H.R. de
2004-03-12
Increased vesicle recycling in response to osmotic cell swelling. Cause and consequence of hypotonicity-provoked ATP release. (Article)
Wijk, Th. van der Tomassen, S.F.B. Houtsmuller, A.B. Jonge, H.R. de Tilly, B.C.
2003-10-10
Osmotic cell swelling-induced ATP release mediates the activation of extracellular signal-regulated protein kinase (Erk)-1/2 but not the activation of osmo-sensitive anion channels (Article)
Wijk, Th. van der Jonge, H.R. de Tilly, B.C.
1999-01-01
Membrane targeting of cGMP-dependent protein kinase is required for cystic fibrosis transmembrane conductance regulator Cl- channel activation (Article)
Vaandrager, A.B. Smolenski, A. Tilly, B.C. Houtsmuller, A.B. Ehlert, E.M.E. Bot, A.G. Edixhoven, M.J. Boomaars, W.E. Lohmann, S.M. Jonge, H.R. de
1998-01-01
Osmotic swelling-induced activation of the extracellular-signal-regulated protein kinases Erk-1 and Erk-2 in intestine 407 cells involves the Ras/Raf-signalling pathway (Article)
Wijk, Th. van der Dorrestijn, J. Narumiya, S. Maassen, J.A. Jonge, H.R. de Tilly, B.C.
1998-01-01
cGMP stimulation of cystic fibrosis transmembrane conductance regulator Cl- channels co-expressed with cGMP-dependent protein kinase type II but not type Ibeta (Article)
Vaandrager, A.B. Lohmann, S.M. Jarchau, T. Walter, U. Jonge, H.R. de Poller, W.C. Tilly, B.C. Smolenski, A. Schneider-Rasp, S. Bot, A.G. Edixhoven, M.J. Scholte, B.J.
1997-01-01
Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances (Article)
Tilly, B.C. Berghe, N. van den Tertoolen, L.G. Edixhoven, M.J. Jonge, H.R. de
1993-01-01
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